Category Archives: Journal Club

Title: Vitamin D and cancer Authors: L Vuolo, C Di Somma, A Faggiano, A Colao – frontiers in endo Date of Publication: 23 April 2012 Type of Paper: Review  What are the main points:  Increased serum calcidiol and Calcitriol are associated with decreased cancer incidence and decreased cancer aggressiveness  What are the general findings:  Vit D mayContinue reading “Serrano Journal Club 4”

Paper: Creatine as a Candidate to Prevent Statin Myopathy Authors: M Balestrino, E AdrianoPublish Date: July 2, 2019 What are the main points:  Statins inhibit guanidinoacetate methyl transferase (GAMT) – last enzyme in creatine synthesis, thus decreasing intracellular content  Could be part of mitochondrial impairment – creatine final acceptor of phosphate in mitochondrial ox phos  CreatineContinue reading “Journal Club Week 2”

Paper: Gut Microbiota in dementia. Critical review of novel findings and their potential application – Luc, Misiak, Pawlowski, et al 2020 What are the main points –  Gut Microbiome is linked with dementia and Alzhemiers  Infectious agents linked with dementia – herpes, H pylori, bacteria causing gingivitis Supplement with lactobacillus and bifidobacterium probiotics may helpContinue reading “Serrano Journal Club 1”